Haemophilia A (Factor VIII deficiency)
Haemophilia A (Factor VIII deficiency)
General description
The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.
Breeds
Boxer, German Shepherd Dog, Labrador Retriever, Old English Sheepdog, Rhodesian Ridgeback
Order details
Test number | 8689 |
Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
Test duration | 5-7 working days |
Test specifications
Inheritance | X-linked recessive |
Detailed description
The underlying pathomechanism of Haemophilia A is a lack or decreased activity of factor VIII that plays a critical role in the coagulation cascade. Affected dogs present with hemorrhage that can vary from mild to severe depending on the degree of the disease. The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.