{"id":228349,"date":"2024-09-12T07:23:52","date_gmt":"2024-09-12T05:23:52","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/osteochondrodysplasie"},"modified":"2024-09-12T07:23:52","modified_gmt":"2024-09-12T05:23:52","slug":"osteochondrodysplasie","status":"publish","type":"page","link":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/erbkrankheiten-katze\/osteochondrodysplasie\/","title":{"rendered":"Osteochondrodysplasie"},"content":{"rendered":"<div class=\"wrap-top\"><div class=\"wrap-left\"><h1 class=\"header-1\">Osteochondrodysplasie<\/h1><h4><strong>General description<\/strong><\/h4><p class=\"bodytext\">Eine Mutation im TRPV4-Gen f\u00fchrt zu den charakteristisch nach vorne gefalteten Ohren bei der Scottish Fold. Au\u00dferdem beg\u00fcnstigt diese Mutation die Ausbildung einer Osteochondrodysplasie, die sich in Missbildungen der Knochen und Gelenke in den distalen Gliedma\u00dfen und dem Schwanz \u00e4u\u00dfert. <\/p><h4 class=\"header-4\"><strong><span>Breeds<\/span><\/strong><\/h4><p>Scottish Fold Longhair, Scottish Fold Shorthair<\/p><\/div><div class=\"wrap-right\"><div class=\"wrap-toggle\"><div class=\"toggle-details\"><details><summary class=\"summary-details\">Order details<\/summary><table border=\"0\"><tr><td width=\"45%\"><span><strong>Test number<\/strong><\/span><\/td><td>8349<\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>OCD<\/td><\/tr><tr><td><strong>Sample material<\/strong><\/td><td>0,5 ml EDTA Blut, 2x Backenabstrich, 1x Spezialabstrich (eNAT)<\/td><\/tr><tr><td><strong>Test duration<\/strong><\/td><td>7-14 Werktage<\/td><\/tr><\/table><\/details><details><summary class=\"summary-specs\">Test specifications<\/summary><table border=\"0\"><tr><td width=\"45%\"><strong>Symptom complex<\/strong><\/td><td>skeletal<\/td><\/tr><tr><td width=\"45%\"><strong>Inheritance<\/strong><\/td><td>autosomal-dominant<\/td><\/tr><tr><td width=\"45%\"><strong>Causality<\/strong><\/td><td>urs\u00e4chlich<\/td><\/tr><tr><td width=\"45%\"><strong>Gene<\/strong><\/td><td>TRPV4<\/td><\/tr><tr><td width=\"45%\"><strong>Mutation<\/strong><\/td><td>C-A<\/td><\/tr><tr><td width=\"45%\"><strong>Literature<\/strong><\/td><td><a href='https:\/\/www.omia.org\/OMIA000319\/9685\/' target='_blank'>OMIA:000319-9685<\/a><\/td><\/tr><\/table><\/details><\/div><div class=\"order-now\"><strong><a href=\"https:\/\/shop.labogen.com\">Order now ...<\/a><\/strong><\/div><\/div><\/div><div class=\"clear-both\"><\/div><\/div><div class=\"wrap-detailed\"><details><summary class=\"detail-summary\">Detailed description<\/summary><p class=\"detailed\"><p>Eine Genvariante im <em>TRPV4<\/em>-Genmutation f\u00fchrt zu den charakteristisch nach vorne <strong>gefalteten Ohren<\/strong> bei der Schottischen Faltohrkatze. Au\u00dferdem kann die genetische Variante ebenfalls zur Ausbildung einer <strong>Osteochondrodysplasie<\/strong> bei betroffenen Katzen f\u00fchren, die sich in <strong>Knochenmissbildungen in den unteren Teilen der Beine, Gelenke und Pfoten sowie dem Schwanz<\/strong> \u00e4u\u00dfert. Homozygot betroffene Katzen entwickeln schwere Missbildungen.<\/p><p>Das Zustandekommen homozygot betroffener Tiere gilt in Deutschalnd als \"Qualzucht\" und eine Verpaarung von zwei Tr\u00e4gertieren ist somit gesetzlich verboten. <\/p><\/p><\/details>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6265,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-228349","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/228349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/comments?post=228349"}],"version-history":[{"count":0,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/228349\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/6265"}],"wp:attachment":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/media?parent=228349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}