{"id":218493,"date":"2024-09-12T07:23:50","date_gmt":"2024-09-12T05:23:50","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/late-onset-ataxie-loa"},"modified":"2024-09-12T07:23:50","modified_gmt":"2024-09-12T05:23:50","slug":"late-onset-ataxie-loa","status":"publish","type":"page","link":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/erbkrankheiten-hund\/late-onset-ataxie-loa\/","title":{"rendered":"Late onset Ataxie (LOA)"},"content":{"rendered":"

Late onset Ataxie (LOA)<\/h1>

General description<\/strong><\/h4>

Von LOA betroffene Tiere zeigen anf\u00e4nglich Koordinationsproblemen und Gleichgewichtsprobleme. Danach kann es bis zur v\u00f6lligen Bewegungsunf\u00e4higkeit f\u00fchren. Betroffene Tiere entwickeln die Symptome in der Regel zwischen dem 6. und 12. Lebensmonat.<\/p>

Breeds<\/span><\/strong><\/h4>

Jack Russell Terrier, Parson Russell Terrier<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8493<\/td><\/tr>
Abbreviation<\/strong><\/td>LOA<\/td><\/tr>
Sample material<\/strong><\/td>0,5 ml EDTA Blut, 2x Backenabstrich, 1x Spezialabstrich (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 Werktage<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>neurologisch<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal-rezessiv<\/td><\/tr>
Age of onset<\/strong><\/td>6-12 Monate<\/td><\/tr>
Causality<\/strong><\/td>urs\u00e4chlich<\/td><\/tr>
Gene<\/strong><\/td>CAPN1<\/td><\/tr>
Mutation<\/strong><\/td>C-T<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001820-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Die Symptome der Erbkrankheit namens Late onset Ataxie (LOA) zeigen sich bereits im Alter von 6 bis 12 Monaten im Bewegungsapparat und werden fortschreitend schlimmer. Anfangs sind Koordinationsprobleme zu erkennen, sp\u00e4ter Probleme mit dem Gleichgewicht bis zu v\u00f6lliger Bewegungsunf\u00e4higkeit. Die Ursache liegt in einer Mutation im calcium activated neutral proteinase (CAPN1)-Gen.<\/p><\/details>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218493","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/comments?post=218493"}],"version-history":[{"count":0,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218493\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/media?parent=218493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}