{"id":218333,"date":"2024-09-12T07:23:49","date_gmt":"2024-09-12T05:23:49","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/progressive-retinaatrophie-crd2-pra"},"modified":"2024-09-12T07:23:49","modified_gmt":"2024-09-12T05:23:49","slug":"progressive-retinaatrophie-crd2-pra","status":"publish","type":"page","link":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/erbkrankheiten-hund\/progressive-retinaatrophie-crd2-pra\/","title":{"rendered":"Progressive Retinaatrophie (crd2-PRA)"},"content":{"rendered":"<div class=\"wrap-top\"><div class=\"wrap-left\"><h1 class=\"header-1\">Progressive Retinaatrophie (crd2-PRA)<\/h1><h4><strong>General description<\/strong><\/h4><p class=\"bodytext\">Bei dieser Form  der PRA kommt es  zu einer Zerst\u00f6rung der Zapfenrezeptorzellen und somit zu einer zunehmenden Tagblindheit und dem Verlust des Farbsehens. Die St\u00e4bchenzellen bleiben dagegen weitestgehend erhalten. Im Alter von 1-2 Jahren  kommt es meist zur vollst\u00e4ndigen Auspr\u00e4gung der Tagblindheit.<\/p><h4 class=\"header-4\"><strong><span>Breeds<\/span><\/strong><\/h4><p>American Pitbull Terrier<\/p><\/div><div class=\"wrap-right\"><div class=\"wrap-toggle\"><div class=\"toggle-details\"><details><summary class=\"summary-details\">Order details<\/summary><table border=\"0\"><tr><td width=\"45%\"><span><strong>Test number<\/strong><\/span><\/td><td>8333<\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>crd2-PRA<\/td><\/tr><tr><td><strong>Sample material<\/strong><\/td><td>0,5 ml EDTA Blut, 2x Backenabstrich, 1x Spezialabstrich (eNAT)<\/td><\/tr><tr><td><strong>Test duration<\/strong><\/td><td>7-14 Werktage<\/td><\/tr><\/table><\/details><details><summary class=\"summary-specs\">Test specifications<\/summary><table border=\"0\"><tr><td width=\"45%\"><strong>Symptom complex<\/strong><\/td><td>ophtalmisch<\/td><\/tr><tr><td width=\"45%\"><strong>Inheritance<\/strong><\/td><td>autosomal-rezessiv<\/td><\/tr><tr><td width=\"45%\"><strong>Age of onset<\/strong><\/td><td>1-2 Jahre <\/td><\/tr><tr><td width=\"45%\"><strong>Causality<\/strong><\/td><td>urs\u00e4chlich<\/td><\/tr><tr><td width=\"45%\"><strong>Gene<\/strong><\/td><td>IQCB1<\/td><\/tr><tr><td width=\"45%\"><strong>Mutation<\/strong><\/td><td>INS<\/td><\/tr><tr><td width=\"45%\"><strong>Literature<\/strong><\/td><td><a href='https:\/\/www.omia.org\/OMIA001675\/9615\/' target='_blank'>OMIA:001675-9615<\/a><\/td><\/tr><\/table><\/details><\/div><div class=\"order-now\"><strong><a href=\"https:\/\/shop.labogen.com\">Order now ...<\/a><\/strong><\/div><\/div><\/div><div class=\"clear-both\"><\/div><\/div><div class=\"wrap-detailed\"><details><summary class=\"detail-summary\">Detailed description<\/summary><p class=\"detailed\">Bei dieser fotschreitenden (progessiven) Erbkrankheit wird die Netzhaut (Retina) des Auges zerst\u00f6rt. Dadurch verliert der betroffene Hund zuerst die F\u00e4higkeit des Farbsehens, da als erstes die sogenannten Zapfen zerst\u00f6rt werden. Der Hund leidet dann an der sogenannten Tagblindheit. Die St\u00e4bchen, die f\u00fcr die Nachtsicht (schwarz-wei\u00df) verantwortlich sind, bleiben vorerst gr\u00f6\u00dftenteils erhalten. Schlie\u00dflich kommt es jedoch im Alter von 1-2 Jahren meist zu einer vollst\u00e4ndigen Erblindung. <\/p><\/details>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218333","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/comments?post=218333"}],"version-history":[{"count":0,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218333\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/media?parent=218333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}