{"id":218309,"date":"2024-09-12T07:23:49","date_gmt":"2024-09-12T05:23:49","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/progressive-retinaatrophie-rcd2-pra"},"modified":"2024-09-12T07:23:49","modified_gmt":"2024-09-12T05:23:49","slug":"progressive-retinaatrophie-rcd2-pra","status":"publish","type":"page","link":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/erbkrankheiten-hund\/progressive-retinaatrophie-rcd2-pra\/","title":{"rendered":"Progressive Retinaatrophie (rcd2-PRA)"},"content":{"rendered":"<div class=\"wrap-top\"><div class=\"wrap-left\"><h1 class=\"header-1\">Progressive Retinaatrophie (rcd2-PRA)<\/h1><h4><strong>General description<\/strong><\/h4><p class=\"bodytext\">Die \"Collie-PRA\" oder auch genannt rod-cone Dysplasie Typ 2 (rcd2) f\u00fchrt durch eine abnorme Entwicklung der Zapfen und St\u00e4bchen zu einem fr\u00fchzeitigen Auftreten der Nachblindheit, die typischerweise bei den Welpen etwa im Alter von 6 Wochen erstmalig auftritt. In den meisten F\u00e4llen erblindet ein rcd2-betroffener Hund im Alter von einem Jahr vollst\u00e4ndig. <\/p><h4 class=\"header-4\"><strong><span>Breeds<\/span><\/strong><\/h4><p>Collie (Kurzhaar\/Langhaar)<\/p><\/div><div class=\"wrap-right\"><div class=\"wrap-toggle\"><div class=\"toggle-details\"><details><summary class=\"summary-details\">Order details<\/summary><table border=\"0\"><tr><td width=\"45%\"><span><strong>Test number<\/strong><\/span><\/td><td>8309<\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>rcd2-PRA<\/td><\/tr><tr><td><strong>Sample material<\/strong><\/td><td>0,5 ml EDTA Blut, 2x Backenabstrich, 1x Spezialabstrich (eNAT)<\/td><\/tr><tr><td><strong>Test duration<\/strong><\/td><td>7-14 Werktage<\/td><\/tr><\/table><\/details><details><summary class=\"summary-specs\">Test specifications<\/summary><table border=\"0\"><tr><td width=\"45%\"><strong>Symptom complex<\/strong><\/td><td>ophtalmisch<\/td><\/tr><tr><td width=\"45%\"><strong>Inheritance<\/strong><\/td><td>autosomal-rezessiv<\/td><\/tr><tr><td width=\"45%\"><strong>Age of onset<\/strong><\/td><td>6 Wochen <\/td><\/tr><tr><td width=\"45%\"><strong>Causality<\/strong><\/td><td>urs\u00e4chlich<\/td><\/tr><tr><td width=\"45%\"><strong>Gene<\/strong><\/td><td>RD3<\/td><\/tr><tr><td width=\"45%\"><strong>Mutation<\/strong><\/td><td>INS<\/td><\/tr><tr><td width=\"45%\"><strong>Literature<\/strong><\/td><td><a href='https:\/\/www.omia.org\/OMIA001260\/9615\/' target='_blank'>OMIA:001260-9615<\/a><\/td><\/tr><\/table><\/details><\/div><div class=\"order-now\"><strong><a href=\"https:\/\/shop.labogen.com\">Order now ...<\/a><\/strong><\/div><\/div><\/div><div class=\"clear-both\"><\/div><\/div><div class=\"wrap-detailed\"><details><summary class=\"detail-summary\">Detailed description<\/summary><p class=\"detailed\">Bei  der \"Collie-PRA\" handelt es sich um eine Ver\u00e4nderung der Netzhaut (rod-cone Dysplasie, rcd2), bei der sich die St\u00e4bchen und Zapfen abnorm entwickeln. In der Folge entwickeln betroffene Hunde ein fr\u00fchzeitige Nachtblindheit. Es sind bereits Welpen ab einem Alter von 6 Wochen betroffen. Nach etwa einem Jahr erblinden die Hunde vollst\u00e4ndig.<\/p><\/details>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218309","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/comments?post=218309"}],"version-history":[{"count":0,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/218309\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/wp-json\/wp\/v2\/media?parent=218309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}