Factor XI deficiency (F11)
Factor XI deficiency (F11)
General description
A mutation in F11 gene leads to factor XI deficiency in Kerry Blue Terriers. Affected dogs sometimes show severe protracted bleeding occurring 12 to 24 hours after surgical interventions. Affected dogs rarely have a mild spontaneous bleeding tendency, and many are asymptomatic.
Breeds
Kerry Blue Terrier
Order details
| Test number | 8809 |
| Abbreviation | F11 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | hematologic |
| Inheritance | autosomal recessive with variable penetrance |
| Causality | causally |
| Gene | F11 |
| Mutation | INS |
| Literature | OMIA:000363-9615 |
Detailed description
A mutation in F11 gene leads to factor XI deficiency in Kerry Blue Terriers. Affected dogs sometimes show severe protracted bleeding occurring 12 to 24 hours after surgical interventions. Affected dogs rarely have a mild spontaneous bleeding tendency, and many are asymptomatic.
