Raine syndrome
Raine syndrome
General description
Raine syndrome is characterized by symptoms similar to those found in craniomadibular osteopathy (CMO). Affected dogs exhibit severe tooth wear resulting in pulpitis and the removal of most teeth. Skeletal bones can also be found to be less mineralized in these dogs.
Breeds
Border Collie
Order details
| Test number | 8394 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | skeletal |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | FAM20C |
| Mutation | G-A |
| Literature | OMIA:002015-9615 |
Detailed description
Raine syndrome is described as an inherited disease with recessive trait in Border Collies. The disease is characterized by symptoms similar to those found in craniomadibular osteopathy (CMO). Affected dogs exhibit severe tooth wear resulting in pulpitis and the removal of most teeth. These symptoms result by hypomineralization of the teeth and weakened enamel. Skeletal bones can also be found to be less mineralized in these dogs.
