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Primary ciliary dyskinesia (PCD)

General description

Primary ciliary dyskinesia (PCD) causes impaired movement of cilia and subsequent health problems in diverse organ systems, notably the respiratory tract.

Breeds

Alaskan Malamute, Australian Shepherd, Miniature American Shepherd, Old English Sheepdog

Order details
Test number8483
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Inheritanceautosomal recessive
Detailed description

Primary ciliary dyskinesia (PCD) belongs to a genetically heterogenous group of inherited ciliopathies, causing impaired movement of cilia and subsequent health problems in diverse organ systems, notably the respiratory tract. Because of the insufficient motility of cilia of epithelial mucous membrane, the function of mucus clearance from the airways is ineffective and results in chronic inflammation of the respiratory tract.

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