Braun (Chocolate/Cinnamon)
Brown (chocolate/cinnamon)
General description
The coat colour chocolate/cinnamon can cause all black pigment to change to a brown colour that can appear either in a darker (chocolate) or a brighter variant (cinnamon).
Order details
| Test number | 8257 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Literature | OMIA:001249-9685 |
Detailed description
The Brown (tyrosinase-related protein-1, TYRP1) gene affects the amount of black (eumelanin) pigment produced. The coat colours chocolate and cinnamon are caused by mutations in the gene TYRP1 (tyrosinase-related protein 1) The wild-type B allele produces normal, black coloration. The b allele produces the brown (chocolate) phenotype and the bl allele produces a light brown or cinnamon phenotype. The brown variants show a suggested allelic series, with the following dominance pattern: B > b > bl. The B allele is dominant and represents the normal “wild type” black coat colour. Cats with “brown” genotypes bb or bbl have a chocolate phenotype, whereas cats with the “light brown” genotype blbl have a cinnamon phenotype.
